SCHEMBL7076258

SCHEMBL7076258

O=CC(CS)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
HIF1A Q16665 1/20 0.39
TAAR1 Q96RJ0 2/20 0.39
SLC6A2 P23975 1/20 0.39
FDPS P14324 1/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH7 P40394 1/20 0.38
CYP1A2 P05177 1/20 0.38
LMNA P02545 1/20 0.36
CYP2D6 P10635 1/20 0.36
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAOB P27338 1/20 0.34
EPHX1 P07099 1/20 0.34
CPA3 P15088 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11848447 0.76 SMN1; SMN2 (0.46) SMN1; SMN2HIF1ATAAR1SLC6A2FDPS
SCHEMBL96457 0.74 TAAR1 (0.52) SMN1; SMN2HIF1ATAAR1SLC6A2FDPS
SCHEMBL541269 0.73 CYP2C19 (0.41) SMN1; SMN2HIF1ATAAR1SLC6A2FDPS
SCHEMBL12265952 0.73 SMN1; SMN2 (0.45) SMN1; SMN2HIF1ATAAR1SLC6A2FDPS
SCHEMBL8026003 0.71 CTSK (0.40) SMN1; SMN2TAAR1SLC6A2CYP2C9CYP2C19
SCHEMBL28416740 0.70 TAAR1 (0.52) SMN1; SMN2HIF1ATAAR1SLC6A2FDPS
SCHEMBL2398268 0.70 SMN1; SMN2 (0.42) SMN1; SMN2HIF1ATAAR1SLC6A2FDPS
SCHEMBL6798782 0.69 EPHX2 (0.41) SMN1; SMN2MEN1KMT2AEPHX2
SCHEMBL11840478 0.67 TAAR1 (0.39) SMN1; SMN2HIF1ATAAR1SLC6A2FDPS
SCHEMBL2421699 0.67 TAAR1 (0.48) SMN1; SMN2HIF1ATAAR1SLC6A2FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed