Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28315429 | 0.82 | LMNA (0.40) | CYP2C19CYP2C9ALDH1A1CYP3A4LMNA | |
| SCHEMBL8026003 | 0.79 | CTSK (0.40) | CYP2C19CYP2C9ALDH1A1CYP3A4LMNA | |
| Ammonia Solution, Strong SCHEMBL27480759 | 0.78 | SMN1; SMN2 (0.43) | CYP2C19CYP2C9ALDH1A1CYP3A4LMNA | |
| SCHEMBL6798782 | 0.77 | EPHX2 (0.41) | SMN1; SMN2CTSKCTSLCTSBMMP8 | |
| SCHEMBL342672 | 0.74 | SLC6A2 (0.45) | CYP2C19CYP2C9ALDH1A1CYP3A4LMNA | |
| SCHEMBL11848447 | 0.74 | SMN1; SMN2 (0.46) | CYP2C19CYP2C9ALDH1A1CYP3A4LMNA | |
| SCHEMBL342641 | 0.73 | — | — | |
| SCHEMBL229942 | 0.73 | — | — | |
| SCHEMBL2516872 | 0.73 | FDPS (0.47) | CYP2C19CYP2C9ALDH1A1CYP3A4LMNA | |
| SCHEMBL7076258 | 0.73 | IDO1 (0.41) | CYP2C19CYP2C9ALDH1A1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414421-A1 | MOISTURE-REACTIVE POLYURETHANE COMPOSITION WITH ACCELERATED CURING ACHIEVED BY THE ACTION OF HEAT | Sika Technology AG (CH) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010112535-A1 | MOISTURE-REACTIVE POLYURETHANE COMPOSITION WITH ACCELERATED CURING ACHIEVED BY THE ACTION OF HEAT | SIKA TECHNOLOGY AG (CH) | 2010-10-07 | — | — | WO | disclosed |
| EP-2132248-A1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | Sika Technology AG (CH) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008116928-A1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | disclosed |