SCHEMBL8026003

SCHEMBL8026003

CCCCC(C=O)(CC)Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 2/20 0.40
CTSL P07711 1/20 0.40
CTSB P07858 1/20 0.40
LMNA P02545 2/20 0.38
CYP2D6 P10635 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SLC6A2 P23975 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
EPHX2 P34913 1/20 0.36
PKM P14618 1/20 0.36
MMP9 P14780 3/20 0.35
MMP13 P45452 3/20 0.35
MMP1 P03956 1/20 0.35
MMP2 P08253 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6798782 0.94 EPHX2 (0.41) CTSKCTSLCTSBSMN1; SMN2SIGMAR1
SCHEMBL28315429 0.90 LMNA (0.40) CTSKCTSLCTSBLMNACYP2D6
SCHEMBL27393019 0.80 LTB4R (0.37) CTSKCTSLCTSBLMNAALDH1A1
SCHEMBL541269 0.79 CYP2C19 (0.41) CTSKCTSLCTSBLMNACYP2D6
SCHEMBL10844227 0.79 EPHX2 (0.38) CTSKSMN1; SMN2SIGMAR1TDP1EPHX2
SCHEMBL624141 0.78 CTSK (0.45) CTSKCTSLCTSBLMNACYP2D6
Ammonia Solution, Strong SCHEMBL27480759 0.76 SMN1; SMN2 (0.43) LMNACYP2D6SMN1; SMN2ALDH1A1CYP3A4
SCHEMBL9578924 0.75 TSHR (0.38) LMNASMN1; SMN2
SCHEMBL11805769 0.75 TSHR (0.38) LMNASMN1; SMN2
SCHEMBL6201251 0.74 LMNA (0.35) LMNAALDH1A1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0982395-A1 Hydroperoxides as perfumes Dragoco Gerberding & Co Aktiengesellschaft (DE) 2000-03-01 EP disclosed
EP-0076493-B1 USE OF 1,1-DI(C1-C6-ALKYL)-2-PHENYL-ETHANE DERIVATIVES AS AROMA CHEMICALS Dragoco Gerberding & Co. GmbH (DE) 1986-08-06 EP disclosed
US-4490284-A ALCOHOLS, ALDEHYDES, AND ESTERS AS ORGANOLEPTIC OILS HAVING A FLOWERY ODOR DRAGOCO GERBERDING & CO. GMBH (DE) 1984-12-25 US disclosed
EP-0076493-A2 Use of 1,1-di(C1-C6-alkyl)-2-phenyl-ethane derivatives as aroma chemicals Dragoco Gerberding & Co. GmbH (DE) 1983-04-13 EP disclosed