Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 17/20 | 0.69 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074180 | 0.88 | CCR2 (0.68) | CCR2TBXA2RABCB11 | |
| SCHEMBL7076520 | 0.87 | CCR2 (0.53) | CCR2ABCB11 | |
| SCHEMBL9239991 | 0.84 | CCR2 (0.67) | CCR2ABCB11 | |
| SCHEMBL7072404 | 0.82 | CCR2 (0.67) | CCR2TBXA2RABCB11 | |
| SCHEMBL6300710 | 0.82 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL7076054 | 0.80 | ABCB11 (0.67) | CCR2ABCB11 | |
| SCHEMBL7079549 | 0.79 | ABCB11 (0.54) | CCR2ABCB11 | |
| SCHEMBL7076795 | 0.79 | CCR2 (0.71) | CCR2ABCB11 | |
| SCHEMBL7072695 | 0.79 | PPARG (0.48) | CCR2 | |
| SCHEMBL7080358 | 0.78 | CCR2 (0.70) | CCR2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003504-B1 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | ASTRAZENECA AB (SE) | 2003-07-02 | — | — | EP | claimed |