Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7071246 | 0.89 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL7076811 | 0.85 | USP2 (0.36) | USP2GAAHSD17B10HTTITGB3 | |
| SCHEMBL7071657 | 0.81 | ITGB3 (0.33) | USP2GAAHSD17B10HTTITGB3 | |
| SCHEMBL7073183 | 0.80 | ITGB3 (0.33) | USP2GAAHSD17B10HTTITGB3 | |
| SCHEMBL7078712 | 0.79 | POLB (0.42) | USP2GAAHSD17B10HTTALOX15 | |
| SCHEMBL7076818 | 0.76 | ALOX15 (0.43) | USP2GAAHSD17B10HTTALOX15 | |
| SCHEMBL7076807 | 0.75 | TERT (0.44) | GAAHSD17B10HTTSMYD3 | |
| SCHEMBL7076629 | 0.75 | GAA (0.41) | GAAITGB3ITGA2BSMYD3 | |
| SCHEMBL7073390 | 0.75 | GAA (0.42) | USP2GAAHSD17B10HTTALOX15 | |
| SCHEMBL7072903 | 0.74 | USP2 (0.41) | USP2GAAHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | WYETH (US) | 2003-06-12 | — | — | US | disclosed |
| US-6429214-B1 | INHIBITORS OF BONE RESORPTION | WYETH | 2002-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | ITGAV, ITGB2, ITGB3 | USP2 2558/4885GAA 2157/4885HSD17B10 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.