Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | F13A1 | P00488 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | TGM1 | P22735 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | PLG | P00747 | 2/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073640 | 0.89 | PLG (0.56) | F13A1TGM2TGM1ALDH1A1PKM | |
| SCHEMBL7075075 | 0.87 | CNR1 (0.56) | F13A1TGM2TGM1ALDH1A1PKM | |
| SCHEMBL7076655 | 0.87 | ALDH1A1 (0.55) | F13A1TGM2TGM1ALDH1A1PKM | |
| SCHEMBL7073594 | 0.86 | PKM (0.72) | ALDH1A1PKMGAASMN1; SMN2LMNA | |
| SCHEMBL7071445 | 0.83 | F10 (0.62) | ALDH1A1GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL7074851 | 0.82 | GAA (0.63) | ALDH1A1PKMGAALMNAF2 | |
| SCHEMBL7074639 | 0.82 | ALDH1A1 (0.55) | ALDH1A1PKMGAASMN1; SMN2LMNA | |
| SCHEMBL7074669 | 0.81 | TSHR (0.56) | ALDH1A1GAASMN1; SMN2LMNAF2 | |
| SCHEMBL7649426 | 0.81 | ALDH1A1 (0.51) | ALDH1A1PKMGAASMN1; SMN2LMNA | |
| SCHEMBL17029140 | 0.81 | POLB (0.72) | F13A1TGM2TGM1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |