Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 15/20 | 0.46 |
| ▸ | PLD2 | O14939 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877005 | 0.86 | PLD1 (0.59) | PLD1PLD2KDM4EHSD17B10DRD2 | |
| SCHEMBL7071351 | 0.83 | PLD1 (0.41) | PLD1PLD2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7136992 | 0.82 | FAAH (0.45) | PLD1PLD2KDM4EHSD17B10DRD2 | |
| SCHEMBL7075659 | 0.78 | PLD1 (0.38) | PLD1PLD2KDM4EDRD2ALDH1A1 | |
| SCHEMBL7075483 | 0.78 | PLD1 (0.39) | PLD1PLD2DRD2DRD3HTR2C | |
| SCHEMBL7774077 | 0.76 | PLD1 (0.53) | PLD1PLD2DRD2ALDH1A1 | |
| SCHEMBL7071160 | 0.76 | PLD1 (0.36) | PLD1PLD2 | |
| SCHEMBL8882719 | 0.75 | HPGD (0.52) | PLD1DRD3DRD4 | |
| SCHEMBL8879126 | 0.75 | MMP13 (0.48) | DRD2DRD3DRD1DRD4HTR2C | |
| SCHEMBL7781108 | 0.75 | PLD1 (0.53) | PLD1PLD2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740658-B1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USED, FOR EXAMPLE, AS NEUROLEPTICS | ABBOTT GMBH & CO KG (DE) | 2003-07-02 | — | — | EP | disclosed |