Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.45 |
| ▸ | DRD3 | P35462 | 6/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | PLD2 | O14939 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882719 | 0.86 | HPGD (0.52) | DRD3PLD1KDM1AHTR1ACYP1A2 | |
| SCHEMBL7076878 | 0.82 | PLD1 (0.46) | DRD3DRD2PLD1ALDH1A1HSD17B10 | |
| SCHEMBL7071351 | 0.82 | PLD1 (0.41) | PLD1ALDH1A1HSD17B10PLD2HTR1A | |
| SCHEMBL7075659 | 0.81 | PLD1 (0.38) | DRD2PLD1ALDH1A1KDM1APLD2 | |
| SCHEMBL7078781 | 0.81 | LMNA (0.41) | DRD3DRD2PLD1ALDH1A1CYP1A2 | |
| SCHEMBL7078780 | 0.79 | MEN1 (0.51) | DRD3 | |
| SCHEMBL7075483 | 0.79 | PLD1 (0.39) | DRD3DRD2PLD1PLD2HTR1A | |
| SCHEMBL7774077 | 0.79 | PLD1 (0.53) | DRD2PLD1ALDH1A1KDM1APLD2 | |
| SCHEMBL7071160 | 0.79 | PLD1 (0.36) | PLD1KDM1APLD2 | |
| SCHEMBL7778725 | 0.78 | PLD1 (0.51) | DRD3PLD1ALDH1A1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740658-B1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USED, FOR EXAMPLE, AS NEUROLEPTICS | ABBOTT GMBH & CO KG (DE) | 2003-07-02 | — | — | EP | disclosed |