Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 11/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.39 |
| ▸ | ITGAV | P06756 | 4/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073100 | 0.94 | ITGB3 (0.43) | PPARDMAOAMAOBPPARGITGB3 | |
| SCHEMBL7076695 | 0.93 | ITGB3 (0.44) | PPARDMAOAMAOBITGB3ITGAV | |
| SCHEMBL7079103 | 0.87 | HTT (0.40) | PPARDLCKMAOAMAOBPPARG | |
| SCHEMBL4623068 | 0.84 | OPRK1 (0.46) | PPARD | |
| Trifluoroacetic Acid SCHEMBL7075230 | 0.83 | AOC3 (0.36) | PPARDLCKMAOAMAOBPPARG | |
| Hydrochloric Acid SCHEMBL7071458 | 0.83 | ITGB3 (0.40) | PPARDMAOAMAOBITGB3ITGAV | |
| Hydrochloric Acid SCHEMBL7071498 | 0.82 | ITGB3 (0.42) | PPARDMAOAMAOBITGB3ITGAV | |
| SCHEMBL3450212 | 0.80 | MAOA (0.50) | PPARDMAOAMAOBPPARGITGB3 | |
| Trifluoroacetic Acid SCHEMBL7075914 | 0.78 | CA12 (0.39) | MAOAMAOBITGB3ITGAVITGA2B | |
| SCHEMBL4621828 | 0.78 | ESR2 (0.43) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | WYETH (US) | 2003-06-12 | — | — | US | disclosed |
| US-6429214-B1 | INHIBITORS OF BONE RESORPTION | WYETH | 2002-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | ITGAV, ITGB2, ITGB3 | PPARD 3395/4885LCK 3138/4885MAOA 2218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.