Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5274661 | 0.99 | CYP1A2 (0.67) | CYP1A2CYP2C19HTTALOX15SMN1; SMN2 | |
| Iodide SCHEMBL3778841 | 0.97 | CYP1A2 (0.65) | CYP1A2CYP2C19HTTALOX15SMN1; SMN2 | |
| SCHEMBL29005884 | 0.90 | CYP1A2 (0.74) | CYP1A2CYP2C19HTTALOX15SMN1; SMN2 | |
| SCHEMBL28638703 | 0.84 | HTT (0.61) | CYP1A2CYP2C19HTTALOX15SMN1; SMN2 | |
| SCHEMBL7092172 | 0.82 | ALOX15 (0.55) | CYP1A2CYP2C19HTTALOX15SMN1; SMN2 | |
| SCHEMBL27509034 | 0.79 | SMN1; SMN2 (0.68) | HTTALOX15SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL6642379 | 0.78 | HTT (0.64) | HTTALOX15SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL6642195 | 0.78 | L3MBTL1 (0.69) | CYP1A2CYP2C19HTTALOX15SMN1; SMN2 | |
| SCHEMBL7829044 | 0.78 | LMNA (0.59) | CYP1A2CYP2C19HTTALOX15SMN1; SMN2 | |
| Bromide SCHEMBL11522514 | 0.77 | SMN1; SMN2 (0.66) | HTTALOX15SMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320571-A1 | 3-SPIRO-CYANIN FLUOROCHROMES AND THEIR USE IN BIOASSAYS | INSTITUT FÜR CHEMO- UND BIOSENSORIK Münster e.V. (DE) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002026890-A1 | 3-SPIRO-CYANIN FLUOROCHROMES AND THEIR USE IN BIOASSAYS | Institut für Chemo- und Biosensorik Münster E.V. (DE) | 2002-04-04 | — | — | WO | disclosed |