SCHEMBL7085983

SCHEMBL7085983

c1ccc([Si](c2ccccc2)(C2CCCCC2)C2CCCCC2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
RAB9A P51151 1/20 0.35
IDO1 P14902 2/20 0.34
SLC18A3 Q16572 1/20 0.34
HPGD P15428 1/20 0.34
POLB P06746 2/20 0.34
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
GAA P10253 2/20 0.34
ALOX15 P16050 1/20 0.34
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
ELANE P08246 1/20 0.33
CYP1A2 P05177 1/20 0.32
GRM5 P41594 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15915044 0.81 ALDH1A1 (0.35) ALDH1A1RAB9AIDO1SLC18A3HPGD
SCHEMBL15914886 0.78 GAA (0.34) ALDH1A1RAB9AIDO1SLC18A3HPGD
SCHEMBL16326803 0.78 GAA (0.34) ALDH1A1RAB9AIDO1SLC18A3HPGD
SCHEMBL1313850 0.77 CYP19A1 (0.37) ALDH1A1RAB9ASLC18A3HPGDPOLB
SCHEMBL2622738 0.77 NR1H2 (0.54) ALDH1A1RAB9AIDO1SLC18A3HPGD
SCHEMBL1776842 0.77 HPGD (0.36) ALDH1A1RAB9AHPGDPOLBCASP3
SCHEMBL1317821 0.77 NOS1 (0.35) ALDH1A1RAB9AIDO1SLC18A3HPGD
SCHEMBL5034194 0.77 ALDH1A1 (0.33) ALDH1A1RAB9AIDO1SLC18A3HPGD
SCHEMBL1776841 0.77 HPGD (0.36) ALDH1A1RAB9AIDO1SLC18A3HPGD
SCHEMBL7077404 0.77 HPGD (0.36) ALDH1A1RAB9AHPGDPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1208167-B1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES HEMPELS SKIBSFARVE FAB J C (DK) 2003-07-30 EP claimed
EP-1208167-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2002-05-29 EP claimed
WO-2000077102-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2000-12-21 WO claimed