Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.53 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047672 | 1.00 | SMPD1 (0.55) | SMPD1NR1H4KAT6AMEN1KMT2A | |
| SCHEMBL7080258 | 0.91 | SMPD1 (0.53) | SMPD1NR1H4KAT6AMEN1KMT2A | |
| SCHEMBL7076275 | 0.91 | SMPD1 (0.53) | SMPD1NR1H4KAT6AMEN1KMT2A | |
| SCHEMBL7083526 | 0.91 | SMPD1 (0.53) | SMPD1NR1H4KAT6AMEN1KMT2A | |
| SCHEMBL7047657 | 0.91 | SMPD1 (0.53) | SMPD1NR1H4KAT6AMEN1KMT2A | |
| SCHEMBL7080208 | 0.91 | SMPD1 (0.53) | SMPD1NR1H4KAT6AMEN1KMT2A | |
| SCHEMBL7076746 | 0.91 | SMPD1 (0.53) | SMPD1NR1H4KAT6AMEN1KMT2A | |
| SCHEMBL7077178 | 0.91 | SMPD1 (0.53) | SMPD1NR1H4KAT6AMEN1KMT2A | |
| SCHEMBL7077945 | 0.91 | SMPD1 (0.53) | SMPD1NR1H4KAT6AMEN1KMT2A | |
| SCHEMBL7080217 | 0.91 | SMPD1 (0.53) | SMPD1NR1H4KAT6AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162818-A1 | Acylsulfonamide derivative | AJINOMOTO CO. INC. (JP) | 2003-08-28 | — | — | US | disclosed |
| US-6555584-B1 | Acetyl-coa carboxylase inhibitors | AJINOMOTO CO., INC. (JP) | 2003-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162818-A1 | Acylsulfonamide derivative | ACSS2, ACACA, FASN | SMPD1 760/4885NR1H4 1199/4885KAT6A 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.