Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047657 | 1.00 | SMPD1 (0.53) | SMPD1ALDH1A1TSHRGAAMEN1 | |
| SCHEMBL7083526 | 1.00 | SMPD1 (0.53) | SMPD1ALDH1A1TSHRGAAMEN1 | |
| SCHEMBL7076275 | 1.00 | SMPD1 (0.53) | SMPD1ALDH1A1TSHRGAAMEN1 | |
| SCHEMBL7080217 | 1.00 | SMPD1 (0.53) | SMPD1ALDH1A1TSHRGAAMEN1 | |
| SCHEMBL7077945 | 1.00 | SMPD1 (0.53) | SMPD1ALDH1A1TSHRGAAMEN1 | |
| SCHEMBL7077178 | 1.00 | SMPD1 (0.53) | SMPD1ALDH1A1TSHRGAAMEN1 | |
| SCHEMBL7080208 | 1.00 | SMPD1 (0.53) | SMPD1ALDH1A1TSHRGAAMEN1 | |
| SCHEMBL7076746 | 1.00 | SMPD1 (0.53) | SMPD1ALDH1A1TSHRGAAMEN1 | |
| SCHEMBL7050498 | 0.99 | SMPD1 (0.52) | SMPD1ALDH1A1TSHRGAAMEN1 | |
| SCHEMBL7083205 | 0.96 | ALDH1A1 (0.52) | SMPD1ALDH1A1TSHRGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162818-A1 | Acylsulfonamide derivative | AJINOMOTO CO. INC. (JP) | 2003-08-28 | — | — | US | disclosed |
| US-6555584-B1 | Acetyl-coa carboxylase inhibitors | AJINOMOTO CO., INC. (JP) | 2003-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162818-A1 | Acylsulfonamide derivative | ACSS2, ACACA, FASN | SMPD1 760/4885ALDH1A1 385/4885TSHR 2829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.