Acetone

Acetone

SCHEMBL7077680

CC(C)=O.CCCCCCCCCCNCCCCCCCCCC

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.68
TSHR P16473 1/20 0.68
S1PR2 O95136 5/20 0.59
S1PR4 O95977 5/20 0.59
S1PR1 P21453 5/20 0.59
S1PR3 Q99500 5/20 0.59
S1PR5 Q9H228 1/20 0.59
EPHX1 P07099 8/20 0.58
PAOX Q6QHF9 1/20 0.58
ADH1B P00325 1/20 0.54
ADH1C P00326 1/20 0.54
ADH1A P07327 1/20 0.54
ADH4 P08319 1/20 0.54
ADH7 P40394 1/20 0.54
CASP2 P42575 1/20 0.52
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
FAAH O00519 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL7079915 1.00 ALDH1A1 (0.68) ALDH1A1TSHRS1PR2S1PR4S1PR1
Acetone SCHEMBL7083131 1.00 ALDH1A1 (0.68) ALDH1A1TSHRS1PR2S1PR4S1PR1
Acetone SCHEMBL7080505 1.00 ALDH1A1 (0.68) ALDH1A1TSHRS1PR2S1PR4S1PR1
Acetic Acid SCHEMBL2513857 0.92 ALDH1A1 (0.65) ALDH1A1TSHRS1PR2S1PR4S1PR1
Acetic Acid SCHEMBL28761306 0.92 ALDH1A1 (0.65) ALDH1A1TSHRS1PR2S1PR4S1PR1
Acetic Acid SCHEMBL6391178 0.92 ALDH1A1 (0.65) ALDH1A1TSHRS1PR2S1PR4S1PR1
Acetic Acid SCHEMBL28014546 0.92 ALDH1A1 (0.65) ALDH1A1TSHRS1PR2S1PR4S1PR1
Acetic Acid SCHEMBL6397604 0.92 ALDH1A1 (0.65) ALDH1A1TSHRS1PR2S1PR4S1PR1
Acetic Acid SCHEMBL6396718 0.92 ALDH1A1 (0.65) ALDH1A1TSHRS1PR2S1PR4S1PR1
Acetic Acid SCHEMBL28423657 0.92 ALDH1A1 (0.65) ALDH1A1TSHRS1PR2S1PR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030118520-A1 Cleaning composition for dental prostheses CLARIANT GMBH (DE) 2003-06-26 US disclosed
US-20020122775-A1 Cleaning compostion for dental prostheses CLARIANT GMBH 2002-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118520-A1 Cleaning composition for dental prostheses NOXO1, AOX1, AOC1 ALDH1A1 807/4885TSHR 4095/4885S1PR2 3778/4885
US-20020122775-A1 Cleaning compostion for dental prostheses NOXO1, AOX1, AOC1 ALDH1A1 978/4885TSHR 3635/4885S1PR2 4340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.