Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080947 | 0.90 | REN (0.45) | RENPDE4BKDM1AMAOAMAOB | |
| SCHEMBL7076588 | 0.89 | REN (0.44) | RENKDM1AMAOAMAOBTACR1 | |
| SCHEMBL7083194 | 0.89 | REN (0.47) | RENPDE4BNR1H2 | |
| SCHEMBL7079844 | 0.87 | REN (0.51) | RENKDM1AMAOAMAOB | |
| SCHEMBL7081735 | 0.85 | REN (0.63) | REN | |
| SCHEMBL7078693 | 0.84 | REN (0.49) | REN | |
| SCHEMBL4602561 | 0.84 | REN (0.44) | RENPDE4B | |
| SCHEMBL6953620 | 0.84 | REN (0.44) | RENPDE4B | |
| SCHEMBL6041963 | 0.83 | REN (0.45) | RENKDM1AMAOAMAOBTACR1 | |
| SCHEMBL6952773 | 0.83 | REN (0.55) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |