Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 10/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ME2 | P23368 | 3/20 | 0.35 |
| ▸ | ME1 | P48163 | 3/20 | 0.35 |
| ▸ | ME3 | Q16798 | 3/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602861 | 0.73 | MAPT (0.50) | ALDH1A1KDM4EMAPTPKMGAA | |
| SCHEMBL30593301 | 0.72 | KDM4E (0.43) | ALDH1A1KDM4EMAPTPKMGAA | |
| SCHEMBL29771306 | 0.67 | DRD4 (0.41) | ALDH1A1KDM4EMAPTPKMGAA | |
| SCHEMBL14765211 | 0.64 | KDM4E (0.44) | ALDH1A1KDM4EMAPTPKMGAA | |
| SCHEMBL21845861 | 0.61 | KDM4E (0.37) | ALDH1A1KDM4EMAPTGAAKMT2A | |
| SCHEMBL13591209 | 0.60 | MEN1 (0.52) | KDM4EMAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL7041242 | 0.59 | MAPT (0.68) | ALDH1A1KDM4EMAPTPKMGAA | |
| SCHEMBL14764930 | 0.59 | KDM4E (0.45) | ALDH1A1KDM4EMAPTPKMGAA | |
| SCHEMBL12155872 | 0.59 | MAPT (0.59) | ALDH1A1KDM4EMAPTPKMGAA | |
| SCHEMBL7308857 | 0.59 | GAA (0.66) | ALDH1A1MAPTGAAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077975-B1 | WATER SOLUBLE AZOLES AS BROAD-SPECTRUM ANTIFUNGALS | JANSSEN PHARMACEUTICA NV (BE) | 2003-04-23 | — | — | EP | disclosed |