Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | ESRRB | O95718 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602861 | 0.86 | MAPT (0.50) | KDM4EMAPTALDH1A1PKMGAA | |
| SCHEMBL20644666 | 0.83 | NOTUM (0.33) | MAPT | |
| SCHEMBL29771306 | 0.82 | DRD4 (0.41) | KDM4EMAPTALDH1A1PKMGAA | |
| SCHEMBL14765211 | 0.75 | KDM4E (0.44) | KDM4EMAPTALDH1A1PKMGAA | |
| SCHEMBL21845861 | 0.73 | KDM4E (0.37) | KDM4EMAPTALDH1A1GAALMNA | |
| SCHEMBL29771380 | 0.72 | MAPT (0.36) | KDM4EMAPTALDH1A1GAALMNA | |
| SCHEMBL7077906 | 0.72 | ALDH1A1 (0.38) | KDM4EMAPTALDH1A1PKMGAA | |
| SCHEMBL14764930 | 0.69 | KDM4E (0.45) | KDM4EMAPTALDH1A1PKMGAA | |
| SCHEMBL12067678 | 0.69 | MAPT (0.77) | KDM4EMAPTALDH1A1PKMGAA | |
| Bromide SCHEMBL11208376 | 0.66 | KDM4E (0.67) | KDM4EMAPTALDH1A1PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789656-A | Preparation method of posaconazole impurity | 山东济坤生物制药有限公司 | 2023-09-22 | — | — | CN | disclosed |