Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861935 | 0.81 | MAPT (0.58) | MAPTMCOLN3HTTNPSR1L3MBTL1 | |
| SCHEMBL2008337 | 0.81 | MAPT (1.00) | MAPTMCOLN3HTTNPSR1L3MBTL1 | |
| SCHEMBL18031174 | 0.80 | MAPT (0.82) | MAPTMCOLN3HTTNPSR1L3MBTL1 | |
| SCHEMBL6302212 | 0.80 | MAPT (0.82) | MAPTMCOLN3HTTNPSR1L3MBTL1 | |
| SCHEMBL6295701 | 0.78 | HSD17B1 (0.74) | MAPTMCOLN3HTTNPSR1L3MBTL1 | |
| SCHEMBL6828525 | 0.75 | MAPT (0.61) | MAPTMCOLN3HTTNPSR1L3MBTL1 | |
| SCHEMBL5925507 | 0.74 | MAPT (0.52) | MAPTMCOLN3HTTNPSR1L3MBTL1 | |
| SCHEMBL24125059 | 0.73 | MAPT (0.82) | MAPTMCOLN3HTTNPSR1L3MBTL1 | |
| SCHEMBL17174235 | 0.73 | MAPT (0.82) | MAPTMCOLN3HTTNPSR1L3MBTL1 | |
| SCHEMBL6828487 | 0.73 | MAPT (0.82) | MAPTMCOLN3HTTNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068204-A1 | SYNTHESIS OF SUBSTITUTED SULFONYL AMINES | Grünenthal GmbH (DE) | 2003-08-21 | — | — | WO | disclosed |