Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.40 |
| ▸ | CTSK | P43235 | 13/20 | 0.40 |
| ▸ | CTSB | P07858 | 11/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | CTSC | P53634 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076976 | 0.99 | CTSS (0.40) | CTSSCTSKCTSBS1PR1S1PR3 | |
| SCHEMBL7072668 | 0.96 | CTSS (0.41) | CTSSCTSKCTSBCTSCCTSL | |
| SCHEMBL5357550 | 0.91 | CTSS (0.42) | CTSSCTSKCTSBCTSCCTSL | |
| SCHEMBL5357510 | 0.84 | CTSS (0.39) | CTSSCTSKCTSBCTSC | |
| SCHEMBL5368724 | 0.84 | CTSS (0.53) | CTSSCTSKCTSBCTSCCTSL | |
| Hydrochloric Acid SCHEMBL6095937 | 0.83 | CTSS (0.52) | CTSSCTSKCTSBCTSCCTSL | |
| SCHEMBL4840267 | 0.82 | CTSS (0.41) | CTSSCTSKCTSBCTSCCTSL | |
| SCHEMBL7075630 | 0.81 | CTSS (0.48) | CTSSCTSL | |
| SCHEMBL8296697 | 0.81 | CTSC (0.50) | CTSSCTSKCTSBCTSCCTSL | |
| SCHEMBL5364139 | 0.80 | CTSK (0.42) | CTSSCTSKCTSBCTSCCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225270-A1 | Compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-12-04 | — | — | US | disclosed |
| US-20030225271-A1 | Compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-12-04 | — | — | US | disclosed |
| US-20020058809-A1 | Compounds useful as reversible inhibitors of cysteine proteases | EMMANUEL MICHEL JOSE (US) | 2002-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058809-A1 | Compounds useful as reversible inhibitors of cysteine proteases | CTSS, CTSK, CTSB | CTSS 1/4885CTSK 2/4885CTSB 3/4885 |
| US-20030225270-A1 | Compounds useful as reversible inhibitors of cysteine proteases | CTSS, CTSK, CTSB | CTSS 1/4885CTSK 2/4885CTSB 3/4885 |
| US-20030225271-A1 | Compounds useful as reversible inhibitors of cysteine proteases | CTSS, CTSK, CTSB | CTSS 1/4885CTSK 2/4885CTSB 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.