Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CRY1 | Q16526 | 3/20 | 0.38 |
| ▸ | CRY2 | Q49AN0 | 3/20 | 0.38 |
| ▸ | PER2 | O15055 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332751 | 0.82 | ALDH1A1 (0.60) | CYP2C9NR1I2HIF1AALDH1A1SMN1; SMN2 | |
| SCHEMBL8243641 | 0.80 | HIF1A (0.67) | CYP2C9NR1I2HIF1A | |
| SCHEMBL3958416 | 0.80 | CYP2C9 (0.48) | CYP2C9NR1I2HIF1APLK1CNR1 | |
| SCHEMBL3959350 | 0.80 | CYP2C9 (0.48) | CYP2C9NR1I2HIF1APLK1CNR1 | |
| SCHEMBL4137380 | 0.80 | CYP2C9 (0.55) | CYP2C9NR1I2HIF1APLK1PER2 | |
| SCHEMBL5335435 | 0.79 | ALDH1A1 (0.57) | CYP2C9NR1I2HIF1AALDH1A1SMN1; SMN2 | |
| SCHEMBL5330885 | 0.79 | ALDH1A1 (0.56) | CYP2C9NR1I2HIF1ACNR1ALDH1A1 | |
| SCHEMBL8247183 | 0.77 | HIF1A (0.62) | CYP2C9NR1I2HIF1A | |
| SCHEMBL8245604 | 0.76 | HIF1A (0.61) | CYP2C9NR1I2HIF1A | |
| SCHEMBL6689094 | 0.74 | CYP2C9 (0.76) | CYP2C9NR1I2PLK1CRY1CRY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059356-A2 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-24 | — | — | WO | claimed |
| WO-2003059356-A2 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |