Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24685295 | 0.83 | MEN1 (0.64) | GAAALDH1A1L3MBTL1USP2NPSR1 | |
| SCHEMBL8326064 | 0.83 | GAA (1.00) | GAAALDH1A1L3MBTL1USP2NPSR1 | |
| SCHEMBL29801234 | 0.83 | MEN1 (0.64) | GAAALDH1A1L3MBTL1USP2NPSR1 | |
| SCHEMBL7531532 | 0.82 | HTT (0.64) | GAAALDH1A1L3MBTL1USP2NPSR1 | |
| SCHEMBL7082686 | 0.81 | TSHR (0.73) | GAAALDH1A1USP2NPSR1LMNA | |
| SCHEMBL13451018 | 0.81 | CA2 (0.63) | GAAALDH1A1L3MBTL1USP2NPSR1 | |
| SCHEMBL31253074 | 0.81 | L3MBTL1 (0.75) | GAAALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL23063879 | 0.81 | L3MBTL1 (0.75) | GAAALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL21246557 | 0.80 | L3MBTL1 (0.55) | GAAALDH1A1L3MBTL1USP2NPSR1 | |
| SCHEMBL21246556 | 0.80 | NAMPT (0.59) | GAAALDH1A1L3MBTL1USP2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030031715-A1 | Pharmaceutical applications of hydrotropic agents, polymers thereof, and hydrogels thereof | PURDUE RESEARCH FOUNDATION | 2003-02-13 | — | — | US | disclosed |
| WO-2002030466-A2 | PHARMACEUTICAL APPLICATIONS OF HYDROTROPIC AGENTS, POLYMERS THEREOF, AND HYDROGELS THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030031715-A1 | Pharmaceutical applications of hydrotropic agents, polymers thereof, and hydrogels thereof | HMGB2, HTT, ABCG2 | GAA 2447/4885ALDH1A1 3603/4885L3MBTL1 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.