Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126436 | 0.84 | GLA (0.48) | MAPTKDM4ESMN1; SMN2ALDH1A1AGBL2 | |
| SCHEMBL26102105 | 0.83 | GLA (0.47) | MAPTKDM4ESMN1; SMN2ALDH1A1AGBL2 | |
| Hydrochloric Acid SCHEMBL26102108 | 0.83 | GLA (0.47) | MAPTKDM4ESMN1; SMN2ALDH1A1AGBL2 | |
| SCHEMBL16389665 | 0.82 | AGBL2 (0.54) | MAPTKDM4ESMN1; SMN2ALDH1A1AGBL2 | |
| SCHEMBL31233701 | 0.82 | NOTUM (0.49) | MAPTKDM4ESMN1; SMN2ALDH1A1AGBL2 | |
| SCHEMBL9928605 | 0.81 | MAPT (0.47) | MAPTKDM4ESMN1; SMN2ALDH1A1AGBL2 | |
| SCHEMBL30134211 | 0.81 | MAPT (0.47) | MAPTKDM4ESMN1; SMN2ALDH1A1AGBL2 | |
| SCHEMBL707320 | 0.79 | ALDH1A1 (0.63) | MAPTKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL15738696 | 0.79 | CFTR (0.57) | MAPTKDM4ESMN1; SMN2ALDH1A1AGBL2 | |
| SCHEMBL22440661 | 0.79 | CFTR (0.47) | KDM4ESMN1; SMN2ALDH1A1AGBL2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118113-B1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA (JP) | 2013-01-30 | — | — | EP | disclosed |
| CN-101611037-B | Pyridyl-triazolopyrimidine derivative or its salt, pesticide containing it and its production process | ISHIHARA SANGYO KAISHA | 2012-11-28 | — | — | CN | disclosed |
| US-8124760-B2 | Pyridyl-triazolopyrimidine derivative or its salt, pesticide containing it and its production process | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20100087452-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD (JP) | 2010-04-08 | — | — | US | disclosed |
| CN-101611037-A | Pyridyl-triazolopyrimidine derivative or its salt, the sterilant that comprises it and its preparation method | ISHIHARA SANGYO KAISHA (JP) | 2009-12-23 | — | — | CN | disclosed |
| EP-2118113-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008099902-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087452-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | SCN5A, CHRNA5, NR5A2 | MAPT 4356/4885KDM4E 1717/4885SMN1; SMN2 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.