Sugi Predict

Sugi Predict / Compounds / SCHEMBL707320

SCHEMBL707320

SCHEMBL707320

CC(=O)c1ncc(C(F)(F)F)cc1Cl

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.63
▸ MAPT P10636 3/20 0.63
▸ HPGD P15428 3/20 0.61
▸ GLA P06280 1/20 0.61
▸ KMT2A Q03164 5/20 0.57
▸ MEN1 O00255 3/20 0.57
▸ LMNA P02545 2/20 0.57
▸ NPSR1 Q6W5P4 3/20 0.52
▸ SMN1; SMN2 Q16637 2/20 0.52
▸ MAPK1 P28482 1/20 0.52
▸ KDM4E B2RXH2 1/20 0.51
▸ GAA P10253 3/20 0.50
▸ HTT P42858 1/20 0.50
▸ XBP1 P17861 1/20 0.49
▸ CYP1A2 P05177 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ CYP2C19 P33261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5212382 0.84 ALDH1A1 (0.65) ALDH1A1MAPTHPGDGLAKMT2A
SCHEMBL286688 0.84 HPGD (0.68) ALDH1A1MAPTHPGDGLAKMT2A
SCHEMBL24198698 0.83 ALDH1A1 (0.59) ALDH1A1MAPTHPGDGLAKMT2A
Hydrochloric Acid SCHEMBL7691125 0.83 HPGD (0.66) ALDH1A1MAPTHPGDGLAKMT2A
SCHEMBL27284155 0.83 ALDH1A1 (0.63) ALDH1A1MAPTHPGDGLAKMT2A
SCHEMBL29827991 0.83 ALDH1A1 (0.73) ALDH1A1MAPTHPGDGLAKMT2A
SCHEMBL1719092 0.83 ALDH1A1 (0.73) ALDH1A1MAPTHPGDGLAKMT2A
SCHEMBL16389665 0.82 AGBL2 (0.54) ALDH1A1MAPTHPGDGLAKMT2A
SCHEMBL14834493 0.82 ALDH1A1 (0.62) ALDH1A1MAPTHPGDGLAKMT2A
SCHEMBL4125681 0.82 MAPK1 (0.59) ALDH1A1MAPTHPGDGLAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836110-A Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethyl pyridine hydrochloride 天津均凯农业科技有限公司 2023-10-03 — — CN claimed
CN-116836110-B Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethyl pyridine hydrochloride 天津均凯农业科技有限公司 2026-02-10 — — CN disclosed
EP-3356387-B1 ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS UNIV MONASH (AU) 2024-06-26 — — EP disclosed
CN-116836110-A Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethyl pyridine hydrochloride 天津均凯农业科技有限公司 2023-10-03 — — CN disclosed
CN-116836110-A Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethyl pyridine hydrochloride 天津均凯农业科技有限公司 2023-10-03 — — CN disclosed
EP-2873658-B1 OXIME-SUBSTITUTED AMIDE COMPOUND AND PEST CONTROL AGENT NISSAN CHEMICAL IND LTD (JP) 2018-09-05 — — EP disclosed
US-9920046-B2 Oxime-substituted amide compound and pest control agent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-20 — — US disclosed
US-9706776-B2 Pesticidally active substituted 5,5-bicyclic heterocycles with sulphur containing substituents SYNGENTA PARTICIPATIONS AG (CH) 2017-07-18 — — US disclosed
US-20170000127-A1 PESTICIDALLY ACTIVE SUBSTITUTED 5,5-BICYCLIC HETEROCYCLES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2017-01-05 — — US disclosed
US-20160318919-A1 OXIME-SUBSTITUTED AMIDE COMPOUND AND PEST CONTROL AGENT NISSAN CHEMICAL INDUSTRIES, LTD (JP) 2016-11-03 — — US disclosed
EP-1548007-A1 2-Pyridinylethylcarboxamide derivatives and their use as fungicides Bayer CropScience S.A. (FR) 2005-06-29 — — EP disclosed
US-20020055639-A1 Pyrazole derivatives as herbicides NEBEL KURT (CH) 2002-05-09 — — US disclosed
US-6274536-B1 CROPS, AGRICULTURE; PRE- AND POSTEMERGENCE SYNGENTA CROP PROTECTION, INC. 2001-08-14 — — US disclosed
US-6204221-B1 Herbicides SYNGENTA CROP PROTECTION, INC. 2001-03-20 — — US disclosed
CN-1250446-A Pyrazole derivatives as herbicides NOVARTIS AG (CH) 2000-04-12 — — CN disclosed
EP-0966461-A1 PYRAZOLE DERIVATIVES AS HERBICIDES Novartis AG (CH) 1999-12-29 — — EP disclosed
CN-1237166-A Pyrazole derivatives useful as herbicides NOVARTIS AG (CH) 1999-12-01 — — CN disclosed
EP-0941222-A2 PYRAZOLE DERIVATIVES USEFUL AS HERBICIDES Novartis AG (CH) 1999-09-15 — — EP disclosed
WO-1998042698-A1 PYRAZOLE DERIVATIVES AS HERBICIDES NOVARTIS AG (CH) 1998-10-01 — — WO disclosed
WO-1998021199-A2 PYRAZOLE DERIVATIVES USEFUL AS HERBICIDES NOVARTIS AG (CH) 1998-05-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020055639-A1 Pyrazole derivatives as herbicides CBR3, HCN1, HCN2 ALDH1A1 901/4885MAPT 4686/4885HPGD 2378/4885
US-20160318919-A1 OXIME-SUBSTITUTED AMIDE COMPOUND AND PEST CONTROL AGENT CHRM1, CHRM2, CHRM4 ALDH1A1 3899/4885MAPT 4458/4885HPGD 3835/4885
US-20170000127-A1 PESTICIDALLY ACTIVE SUBSTITUTED 5,5-BICYCLIC HETEROCYCLES WITH SULPHUR CONTAINING SUBSTITUENTS DDT, ACHE, THOP1 ALDH1A1 1152/4885MAPT 1279/4885HPGD 1464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.