Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMO | Q99835 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793867 | 0.90 | HTT (0.62) | LMNAHTTSMOALDH1A1CHRNB2 | |
| SCHEMBL6793016 | 0.88 | ALDH1A1 (0.61) | LMNAHTTSMOALDH1A1CHRNB2 | |
| SCHEMBL6788071 | 0.86 | KDM4E (0.51) | LMNAHTTSMOALDH1A1CHRNB2 | |
| SCHEMBL6799666 | 0.86 | TDP1 (0.54) | LMNAHTTSMOALDH1A1CHRNB2 | |
| SCHEMBL6794025 | 0.83 | LMNA (0.48) | LMNAHTTSMOALDH1A1CHRNB2 | |
| SCHEMBL6800986 | 0.83 | GAA (0.64) | LMNAHTTSMOALDH1A1MAPT | |
| SCHEMBL6793244 | 0.83 | SMO (0.62) | LMNAHTTSMOALDH1A1SMN1; SMN2 | |
| SCHEMBL6200210 | 0.83 | CHRNB2 (0.66) | LMNAHTTALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL6792646 | 0.82 | LMNA (0.47) | LMNAHTTSMOALDH1A1CHRNB2 | |
| SCHEMBL6788429 | 0.81 | KDR (0.52) | LMNAHTTSMOALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |