Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21812656 | 0.76 | LMNA (0.38) | NPC1RAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL11779488 | 0.75 | LOXL2 (0.52) | HDAC1HDAC6AOC3LOXL2 | |
| SCHEMBL2643234 | 0.74 | LOXL2 (0.42) | HDAC1HDAC6AOC3LOXL2 | |
| SCHEMBL15581369 | 0.71 | CYP1A2 (0.41) | NPC1RAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL2643232 | 0.71 | LOXL2 (0.40) | HDAC1HDAC6AOC3LOXL2 | |
| SCHEMBL17080142 | 0.69 | MAPT (0.44) | NPC1RAB9AL3MBTL1KDM4EGAA | |
| SCHEMBL13593122 | 0.68 | CYP1A2 (0.44) | NPC1RAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL28752153 | 0.68 | AOC3 (0.52) | AOC3NPC1RAB9ATDP1KDM4E | |
| SCHEMBL15581617 | 0.68 | MEN1 (0.41) | NPC1RAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL2643105 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |