Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 9/20 | 0.36 |
| ▸ | NPC1 | O15118 | 7/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5637413 | 0.83 | CYP1A2 (0.45) | LMNARAB9ANPC1L3MBTL1CASP3 | |
| SCHEMBL3129377 | 0.77 | LMNA (0.59) | LMNARAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL7079768 | 0.76 | HDAC1 (0.39) | RAB9ANPC1L3MBTL1CASP3SENP8 | |
| SCHEMBL3124093 | 0.74 | LMNA (0.42) | LMNARAB9AL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL28675112 | 0.70 | CYP1A2 (0.42) | LMNARAB9ANPC1L3MBTL1CASP3 | |
| SCHEMBL25309164 | 0.70 | MEN1 (0.49) | LMNAMAPTGAAPKMALDH1A1 | |
| SCHEMBL3652832 | 0.70 | TLR7 (0.37) | LMNARAB9ANPC1L3MBTL1CASP3 | |
| SCHEMBL20508384 | 0.69 | F2 (0.36) | RAB9ANPC1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL856603 | 0.69 | CYP1A2 (0.32) | RAB9ANPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL28639401 | 0.69 | LMNA (0.36) | LMNAL3MBTL1MAPTNQO1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |
| EP-3628672-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | Antabio SAS (FR) | 2020-04-01 | — | — | EP | disclosed |