Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10577438 | 0.86 | POLB (0.61) | POLBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL2142240 | 0.84 | RAB9A (0.58) | POLBRAB9ANPC1HRH1SMN1; SMN2 | |
| SCHEMBL10578507 | 0.84 | L3MBTL1 (0.51) | L3MBTL1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28144225 | 0.84 | RAB9A (0.65) | L3MBTL1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10577883 | 0.84 | RAB9A (0.65) | POLBRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL10584591 | 0.80 | MEN1 (0.56) | L3MBTL1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL5843113 | 0.79 | MAOB (0.58) | L3MBTL1MAOAMAOBRAB9ANPC1 | |
| SCHEMBL5272776 | 0.78 | GFER (0.50) | MAOAMAOBRAB9AKMT2AALDH1A1 | |
| SCHEMBL2064520 | 0.78 | HRH1 (0.52) | POLBRAB9ANPC1HRH1SMN1; SMN2 | |
| SCHEMBL10573100 | 0.77 | MEN1 (0.48) | L3MBTL1POLBRAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |