Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.34 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 3/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31387587 | 0.85 | L3MBTL3 (0.51) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BJAK3 | |
| SCHEMBL31387583 | 0.85 | L3MBTL3 (0.51) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BJAK3 | |
| SCHEMBL14562667 | 0.79 | L3MBTL3 (0.53) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BHDAC4 | |
| SCHEMBL15695604 | 0.75 | BTK (0.46) | L3MBTL3JAK3TEAD1KDM1ABTK | |
| SCHEMBL19502758 | 0.75 | L3MBTL3 (0.49) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BHDAC4 | |
| SCHEMBL425964 | 0.75 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BHDAC4 | |
| SCHEMBL27781047 | 0.74 | L3MBTL3 (0.60) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BHDAC4 | |
| SCHEMBL4550247 | 0.72 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1 | |
| SCHEMBL3104303 | 0.72 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BHDAC4 | |
| SCHEMBL2575592 | 0.72 | ATM (0.41) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980368-B1 | 3-(PYRROLIDIN-3-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES AND THEIR USE AS 5-HT4 LIGANDS | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| US-6248757-B1 | ANTISEROTONINE AGENTS | SANOFI-SYNTHELABO (FR) | 2001-06-19 | — | — | US | disclosed |
| EP-0980368-A1 | 3-(PYRROLIDIN-3-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES AND THEIR USE AS 5-HT4 LIGANDS | SANOFI-SYNTHELABO (FR) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998050381-A1 | 3-(PYRROLIDIN-3-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES AND THEIR USE AS 5-HT4 LIGANDS | SANOFI-SYNTHELABO (FR) | 1998-11-12 | — | — | WO | disclosed |