Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.39 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31387587 | 0.82 | L3MBTL3 (0.51) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BBTK | |
| SCHEMBL31387583 | 0.82 | L3MBTL3 (0.51) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BBTK | |
| SCHEMBL19502758 | 0.79 | L3MBTL3 (0.49) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BBTK | |
| SCHEMBL7079828 | 0.79 | L3MBTL3 (0.49) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BBTK | |
| SCHEMBL27781047 | 0.79 | L3MBTL3 (0.60) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BKDM1A | |
| SCHEMBL4550247 | 0.77 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1SMN1; SMN2 | |
| SCHEMBL3104303 | 0.77 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BKDM1A | |
| SCHEMBL8259253 | 0.77 | ALDH1A1 (0.50) | MAOBSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8362221 | 0.75 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BKDM1A | |
| SCHEMBL22878132 | 0.75 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070049594-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049594-A1 | Novel compounds and compositions as cathepsin inhibitors | CTSS, CTSB, CTSE | L3MBTL3 4303/4885L3MBTL1 4113/4885CDYL 1723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.