Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 9/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079059 | 0.84 | ALDH1A1 (0.45) | MMP2ALDH1A1MMP13MMP3PDE4A | |
| SCHEMBL7073376 | 0.83 | ALDH1A1 (0.46) | MMP2ALDH1A1MMP13MMP3PDE4A | |
| SCHEMBL7079124 | 0.82 | ALDH1A1 (0.45) | MMP2ALDH1A1MMP13MMP3PDE4A | |
| SCHEMBL7078814 | 0.82 | MMP13 (0.48) | MMP2MMP9ALDH1A1MMP13MMP3 | |
| SCHEMBL7078648 | 0.79 | FNTA (0.54) | ALDH1A1MMP13MMP1HSD11B1FNTA | |
| SCHEMBL7077837 | 0.79 | ALDH1A1 (0.45) | MMP2ALDH1A1MMP13MMP3PDE4A | |
| SCHEMBL7073742 | 0.79 | KMT2A (0.45) | ALDH1A1HSD11B1FNTAFNTBEEF2K | |
| SCHEMBL7077971 | 0.78 | MMP13 (0.44) | MMP2MMP9ALDH1A1MMP13PDE4A | |
| SCHEMBL7075400 | 0.77 | F2 (0.45) | MMP2MMP9ALDH1A1MMP13KCNA5 | |
| SCHEMBL7073837 | 0.77 | FNTA (0.52) | MMP2MMP9ALDH1A1MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |