Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.52 |
| ▸ | FNTB | P49356 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP14 | P50281 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078814 | 0.85 | MMP13 (0.48) | FNTAFNTBALDH1A1MMP13MMP2 | |
| SCHEMBL7078927 | 0.81 | CA12 (0.44) | FNTAFNTBALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL7077971 | 0.81 | MMP13 (0.44) | FNTAFNTBALDH1A1MMP13MMP2 | |
| SCHEMBL7078648 | 0.81 | FNTA (0.54) | FNTAFNTBALDH1A1MMP13MAPK1 | |
| SCHEMBL7077839 | 0.80 | KDM4E (0.43) | — | |
| SCHEMBL7073376 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MMP13CA12CA9MMP2 | |
| SCHEMBL7079124 | 0.77 | ALDH1A1 (0.45) | FNTAFNTBALDH1A1MMP13MMP2 | |
| SCHEMBL7079059 | 0.77 | ALDH1A1 (0.45) | FNTAFNTBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL7078136 | 0.77 | MMP2 (0.58) | FNTAFNTBCA12CA1CA2 | |
| SCHEMBL7079922 | 0.77 | MMP2 (0.43) | FNTAFNTBALDH1A1MMP13MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |