Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 12/20 | 0.47 |
| ▸ | CTSS | P25774 | 9/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6105765 | 0.88 | CTSL (0.53) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7085808 | 0.86 | CTSL (0.56) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5364061 | 0.84 | CTSK (0.52) | CTSLCTSSCTSKCTSB | |
| SCHEMBL3899922 | 0.81 | CTSS (0.43) | CTSLCTSSEPHX1 | |
| SCHEMBL6974612 | 0.80 | CTSS (0.57) | CTSLCTSSCTSK | |
| SCHEMBL6107882 | 0.75 | CTSS (0.64) | CTSLCTSS | |
| SCHEMBL3895273 | 0.75 | CTSS (0.48) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7690068 | 0.74 | CTSS (0.43) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5362015 | 0.74 | CTSS (0.56) | CTSLCTSSCTSK | |
| SCHEMBL6106482 | 0.73 | CTSL (0.58) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | claimed |