SCHEMBL7080031

SCHEMBL7080031

O=C(O)OC(=O)NSCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.41
IDO1 P14902 3/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HPGD P15428 1/20 0.38
HAO1 Q9UJM8 1/20 0.37
RAB9A P51151 2/20 0.37
HTT P42858 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
NPC1 O15118 1/20 0.36
AKR1B1 P15121 1/20 0.36
PKM P14618 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
FFAR1 O14842 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7074367 0.83 CYP2C19 (0.39) CYP2C19IDO1ALDH1A1LMNASMN1; SMN2
SCHEMBL10589026 0.79 GAA (0.50) CYP2C19ALDH1A1LMNASMN1; SMN2HPGD
SCHEMBL3080810 0.79 CYP2C19 (0.47) CYP2C19IDO1ALDH1A1LMNASMN1; SMN2
SCHEMBL7844886 0.79 SMN1; SMN2 (0.47) CYP2C19IDO1ALDH1A1LMNASMN1; SMN2
Hydrochloric Acid SCHEMBL7874996 0.78 CYP2C19 (0.43) CYP2C19IDO1ALDH1A1LMNASMN1; SMN2
SCHEMBL3074971 0.77 ALDH1A1 (0.46) CYP2C19IDO1ALDH1A1LMNASMN1; SMN2
SCHEMBL7396455 0.76 RAB9A (0.43) CYP2C19ALDH1A1LMNASMN1; SMN2HPGD
SCHEMBL133803 0.76 IDO1 (0.48) CYP2C19IDO1ALDH1A1LMNASMN1; SMN2
SCHEMBL28396949 0.76 CYP2C19 (0.44) CYP2C19ALDH1A1LMNASMN1; SMN2HPGD
Hydrochloric Acid SCHEMBL10690050 0.74 IDO1 (0.50) CYP2C19IDO1ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed