SCHEMBL7080108

SCHEMBL7080108

NC(=O)C(C(N)=O)(C1CCCCC1)C1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 9/20 0.41
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
ALOX5 P09917 2/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAPT P10636 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
EPHX2 P34913 1/20 0.33
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
SSTR4 P31391 1/20 0.32
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29013937 0.97 EPHX1 (0.39) EPHX1CES2CES1ALOX5NPC1
Hydrochloric Acid SCHEMBL4532336 0.95 EPHX1 (0.38) EPHX1CES2CES1ALOX5NPC1
Hydrochloric Acid SCHEMBL4532340 0.95 EPHX1 (0.38) EPHX1CES2CES1ALOX5NPC1
SCHEMBL28465427 0.90 EPHX1 (0.38) EPHX1CES2CES1ALOX5NPC1
SCHEMBL7078828 0.86 EPHX1 (0.35) EPHX1CES2CES1ALOX5NPC1
SCHEMBL28905469 0.81 TSHR (0.38) EPHX1ALOX5NPC1RAB9ASMN1; SMN2
SCHEMBL6316603 0.79 EPHX1 (0.41) EPHX1CES2CES1ALOX5NPC1
SCHEMBL2842403 0.79 EPHX1 (0.41) EPHX1CES2CES1ALOX5NPC1
SCHEMBL10812148 0.77 CES2 (0.42) EPHX1CES2CES1ALOX5NPC1
SCHEMBL8328164 0.76 KEAP1 (0.42) EPHX1CES2CES1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115522052-B Method for recovering rare noble metals in spent fuel post-treatment high-level waste liquid 济南大学 2024-06-25 CN claimed
CN-116425904-A Supported Ziegler-Natta catalyst and preparation method and application thereof 山东京博石油化工有限公司 2023-07-14 CN claimed
EP-3662089-A1 METHOD FOR SEPARATING PALLADIUM FROM OTHER METAL ELEMENTS PRESENT IN AN AQUEOUS NITRIC PHASE USING SPECIFIC MALONAMIDES AS EXTRACTANTS Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2020-06-10 EP claimed
CN-115522052-B Method for recovering rare noble metals in spent fuel post-treatment high-level waste liquid 济南大学 2024-06-25 CN disclosed
CN-115522052-B Method for recovering rare noble metals in spent fuel post-treatment high-level waste liquid 济南大学 2024-06-25 CN disclosed
CN-116425904-A Supported Ziegler-Natta catalyst and preparation method and application thereof 山东京博石油化工有限公司 2023-07-14 CN disclosed
CN-115522052-A Method for recovering rare and precious metals in spent fuel post-treatment high-level radioactive waste liquid 济南大学 2022-12-27 CN disclosed
EP-3662089-A1 METHOD FOR SEPARATING PALLADIUM FROM OTHER METAL ELEMENTS PRESENT IN AN AQUEOUS NITRIC PHASE USING SPECIFIC MALONAMIDES AS EXTRACTANTS Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2020-06-10 EP disclosed
EP-3331852-A1 SUBSTITUTED MALONAMIDES AND THEIR USE AS ANTIBACTERIAL DRUGS National Taiwan University (TW) 2018-06-13 EP disclosed
CN-108026027-A substituted Malonamide compounds and their use as antibacterial agents 邱浩杰 2018-05-11 CN disclosed
WO-2017028745-A1 SUBSTITUTED MALONAMIDES AND THEIR USE AS ANTIBACTERIAL DRUGS SHIAU CHUNG-WAI (CN) 2017-02-23 WO disclosed
CN-103819596-A Preparation method of isotactic poly-1-butene PETROCHINA CO LTD 2014-05-28 CN disclosed
CN-1196716-C Modified particle, support, catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL CO (JP) 2005-04-13 CN disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
CN-1422286-A Modified particle, support, catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL CO (JP) 2003-06-04 CN disclosed