Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973627 | 0.86 | MEN1 (0.40) | MAOAMAOBLMNATSHRTDP1 | |
| SCHEMBL6969333 | 0.86 | DHODH (0.33) | MAOAMAOBALDH1A1LMNAMAPT | |
| SCHEMBL6974087 | 0.86 | SMN1; SMN2 (0.35) | RAB9AMAOAMAOBALDH1A1LMNA | |
| SCHEMBL6974182 | 0.84 | KDM4E (0.34) | ALDH1A1MAPTTDP1 | |
| SCHEMBL7082939 | 0.84 | SMN1; SMN2 (0.31) | ALDH1A1LMNAMAPTSMN1; SMN2PTPN1 | |
| SCHEMBL6971673 | 0.83 | SMN1; SMN2 (0.40) | ALDH1A1LMNAMAPTTSHRSMN1; SMN2 | |
| SCHEMBL6967197 | 0.83 | SLC6A4 (0.34) | RAB9AMAOAMAOBALDH1A1LMNA | |
| SCHEMBL6965584 | 0.83 | MEN1 (0.35) | ALDH1A1LMNAMAPTTDP1SMN1; SMN2 | |
| SCHEMBL7086006 | 0.83 | ALOX5AP (0.33) | RAB9AALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6967795 | 0.83 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |