Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086710 | 0.83 | NR1I2 (0.41) | — | |
| SCHEMBL7133990 | 0.82 | PTPN1 (0.40) | BCL2 | |
| SCHEMBL7083575 | 0.78 | HMGCR (0.63) | HMGCR | |
| SCHEMBL5663542 | 0.74 | PTPN1 (0.47) | BCL2 | |
| SCHEMBL9358736 | 0.74 | HMGCR (0.44) | HMGCR | |
| SCHEMBL19398043 | 0.70 | KDM4E (0.48) | HMGCR | |
| SCHEMBL5668436 | 0.67 | PTPN1 (0.37) | BCL2 | |
| SCHEMBL5668440 | 0.67 | PTPN1 (0.37) | BCL2 | |
| SCHEMBL9749183 | 0.67 | BCL2 (0.54) | BCL2 | |
| SCHEMBL8772360 | 0.65 | HMGB1 (0.56) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326618-A2 | USE OF ARYL-SUBSTITUTED 1,1-DIPHOSPHONATES FOR THE TREATMENT OF BONE DISEASES | Ilex Oncology Research S.A. (CH) | 2003-07-16 | — | — | EP | claimed |
| WO-2002011704-A2 | USE OF ARYL-SUBSTITUTED 1,1-DIPHOSPHONATES FOR THE TREATMENT OF BONE DISEASES | SYMPHAR S.A. (CH) | 2002-02-14 | — | — | WO | claimed |