Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNPH1 | O43598 | 4/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749502 | 0.89 | P2RY2 (0.60) | DNPH1P2RY2P2RY1SRCSMN1; SMN2 | |
| SCHEMBL4079343 | 0.86 | DNPH1 (0.49) | DNPH1P2RY2P2RY1SRCSMN1; SMN2 | |
| SCHEMBL11526724 | 0.86 | DNPH1 (0.49) | DNPH1P2RY2P2RY1SRCSMN1; SMN2 | |
| SCHEMBL4308125 | 0.85 | DNPH1 (0.48) | DNPH1P2RY2P2RY1SRCSMN1; SMN2 | |
| SCHEMBL5783590 | 0.83 | DNPH1 (0.49) | DNPH1P2RY2P2RY1SRCSMN1; SMN2 | |
| SCHEMBL3218639 | 0.82 | DNPH1 (0.46) | DNPH1P2RY2P2RY1SRCSMN1; SMN2 | |
| SCHEMBL10903418 | 0.82 | P2RY2 (0.48) | DNPH1P2RY2P2RY1SRCSMN1; SMN2 | |
| SCHEMBL27938577 | 0.80 | PRMT5 (0.49) | DNPH1P2RY2P2RY1SRCSMN1; SMN2 | |
| SCHEMBL27938581 | 0.80 | PRMT5 (0.49) | DNPH1P2RY2P2RY1SRCSMN1; SMN2 | |
| SCHEMBL8441738 | 0.80 | P2RY2 (0.52) | P2RY2P2RY1SRCSMN1; SMN2P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002100-B1 | METHOD FOR PRODUCING AND IDENTIFYING NEW HYDROLASES HAVING IMPROVED PROPERTIES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2003-07-02 | — | — | EP | disclosed |