SCHEMBL749502

SCHEMBL749502

Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(OOP(=O)(O)O)OP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 4/20 0.60
P2RY1 P47900 4/20 0.60
SRC P12931 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
ADORA1 P30542 2/20 0.60
DNPH1 O43598 1/20 0.60
PRKAB2 O43741 1/20 0.60
TRPM2 O94759 1/20 0.60
LDHA P00338 1/20 0.60
ADRB2 P07550 1/20 0.60
FBP1 P09467 1/20 0.60
PRKAG1 P54619 1/20 0.60
PRKAA2 P54646 1/20 0.60
PDE4D Q08499 1/20 0.60
KCNH2 Q12809 1/20 0.60
PRKAA1 Q13131 1/20 0.60
PDE3A Q14432 1/20 0.60
TAS1R3 Q7RTX0 1/20 0.60
TAS1R1 Q7RTX1 1/20 0.60
P2RY11 Q96G91 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16108843 0.89 P2RY2 (0.61) P2RY2P2RY1SRCSMN1; SMN2ADORA1
SCHEMBL7080308 0.89 DNPH1 (0.46) P2RY2P2RY1SRCSMN1; SMN2ADORA1
SCHEMBL4261443 0.87 P2RY2 (0.64) P2RY2P2RY1SRCSMN1; SMN2ADORA1
SCHEMBL7231385 0.86 P2RY2 (0.64) P2RY2P2RY1SRCSMN1; SMN2ADORA1
SCHEMBL756245 0.86 P2RY2 (0.64) P2RY2P2RY1SRCSMN1; SMN2ADORA1
SCHEMBL1641392 0.85 TAS1R3 (0.65) P2RY2P2RY1SRCSMN1; SMN2ADORA1
SCHEMBL9750489 0.85 P2RY2 (0.56) P2RY2P2RY1SRCSMN1; SMN2ADORA1
Water SCHEMBL443839 0.85 P2RY2 (0.63) P2RY2P2RY1SRCSMN1; SMN2ADORA1
SCHEMBL5320373 0.85 P2RY2 (0.63) P2RY2P2RY1SRCSMN1; SMN2ADORA1
SCHEMBL2791974 0.85 P2RY2 (0.63) P2RY2P2RY1SRCSMN1; SMN2ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2405275-B1 Method for measuring glycated albumin contained in serum or plasma using mannitol as stabiliser for a control serum or plasma. BML INC (JP) 2018-10-10 EP claimed
EP-2222229-B1 DEVICE FOR BIOCHEMICAL PROCESSING AND ANALYSIS OF A SAMPLE LIFEASSAYS AB PUBL (SE) 2013-02-20 EP claimed
EP-1850134-B1 Method and Apparatus for the determination of the Thromboyte function and flow conditions SIEMENS HEALTHCARE DIAGNOSTICS (DE) 2013-01-30 EP claimed
EP-2044212-B1 METHODS FOR IDENTIFYING PATIENTS WITH INCREASED RISK OF AN ADVERSE CARDIOVASCULAR EVENT SIEMENS HEALTHCARE DIAGNOSTICS (US) 2012-03-21 EP claimed
EP-1895303-B1 METHOD OF ASSAYING 1, 5-ANHYDROGLUCITOL BY USING WHOLE BLOOD NIPPON KAYAKU KK (JP) 2011-05-11 EP claimed
EP-1616963-B1 Process for producing dipeptides or dipeptide derivatives KYOWA HAKKO BIO CO LTD (JP) 2009-11-18 EP claimed
EP-1139793-B1 INHIBITORS OF THE BITTER TASTE RESPONSE SINAI SCHOOL MEDICINE (US) 2009-10-14 EP claimed
EP-1753774-B1 2\"-NITROBENZYL-MODIFIED RIBONUCLEOTIDES ASM SCIENT INC (US) 2008-09-10 EP claimed
EP-1850134-A1 Method and Apparatus for the determination of the Thromboyte function and flow conditions Dade Behring Marburg GmbH (DE) 2007-10-31 EP claimed
EP-1850135-A1 Method for determining the thrombocyte function and flow conditions Dade Behring Marburg GmbH (DE) 2007-10-31 EP claimed
WO-1999029895-A1 STABILISED REAGENT AND METHOD FOR DETERMINING CREATINE KINASE ROCHE DIAGNOSTICS GMBH (DE) 1999-06-17 WO claimed
EP-0913483-A2 Method and reagent for the determination of creatine kinase Roche Diagnostics GmbH (DE) 1999-05-06 EP claimed
EP-0566140-B1 Method for producing dinucleoside polyphosphate, nucleoside polyphosphate or derivatives thereof UNITIKA LTD (JP) 1998-07-01 EP claimed
EP-0352477-B1 Use of adenosine 5'-phosphat in the treatment of cancer cachexia RAPAPORT ELIEZER (US) 1995-01-18 EP claimed
EP-0385486-B1 Process for producing fructose-1,6-diphosphate UNITIKA LTD (JP) 1994-06-22 EP claimed
EP-0247819-B1 PROCESS FOR PRODUCING DIADENOSINE TETRAPHOSPHATE AND DERIVATIVES THEREOF UNITIKA LTD. (JP) 1991-07-24 EP claimed
EP-0239222-B1 ANALYTICAL ELEMENT CONTAINING PHOTOSENSITIVE COMPOUND AND FILTER LAYER AND METHOD OF USE EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-12-05 EP claimed
EP-0200541-B1 IMMUNOCHEMICAL METHOD AND ANALYTICAL COMPOSITION AND ELEMENT FOR DETERMINATION OF CREATINE KINASE-MB EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-10-03 EP claimed
EP-0202094-B1 PROCESS FOR PRODUCING PHYSIOLOGICALLY ACTIVE SUBSTANCE UNITIKA LTD. (JP) 1988-09-21 EP claimed
EP-0100022-B1 PHARMACEUTICAL COMPOSITION CONTAINING ADENOSINE DERIVATIVES FOR USE IN TREATING TUMOURS Rapaport, Eliezer (US) 1988-04-20 EP claimed