SCHEMBL4079343

SCHEMBL4079343

O=P(O)(O)OC(O)[C@H]1O[C@@H](n2cnc3c(O)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNPH1 O43598 4/20 0.49
P2RY2 P41231 4/20 0.49
P2RY1 P47900 4/20 0.49
SRC P12931 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
PRKAB2 O43741 1/20 0.49
TRPM2 O94759 1/20 0.49
LDHA P00338 1/20 0.49
ADRB2 P07550 1/20 0.49
FBP1 P09467 1/20 0.49
ADORA1 P30542 1/20 0.49
PRKAG1 P54619 1/20 0.49
PRKAA2 P54646 1/20 0.49
PDE4D Q08499 1/20 0.49
KCNH2 Q12809 1/20 0.49
PRKAA1 Q13131 1/20 0.49
PDE3A Q14432 1/20 0.49
TAS1R3 Q7RTX0 1/20 0.49
TAS1R1 Q7RTX1 1/20 0.49
P2RY11 Q96G91 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11526724 1.00 DNPH1 (0.49) DNPH1P2RY2P2RY1SRCSMN1; SMN2
SCHEMBL4308125 0.88 DNPH1 (0.48) DNPH1P2RY2P2RY1SRCSMN1; SMN2
SCHEMBL756245 0.88 P2RY2 (0.64) DNPH1P2RY2P2RY1SRCSMN1; SMN2
SCHEMBL3852963 0.88 PDE4D (0.49) DNPH1P2RY2P2RY1SRCSMN1; SMN2
Water SCHEMBL443839 0.88 P2RY2 (0.63) DNPH1P2RY2P2RY1SRCSMN1; SMN2
SCHEMBL5783590 0.87 DNPH1 (0.49) DNPH1P2RY2P2RY1SRCSMN1; SMN2
SCHEMBL11525187 0.86 IMPDH2 (0.46) DNPH1P2RY2P2RY1SRCSMN1; SMN2
SCHEMBL3218639 0.86 DNPH1 (0.46) DNPH1P2RY2P2RY1SRCSMN1; SMN2
SCHEMBL7080308 0.86 DNPH1 (0.46) DNPH1P2RY2P2RY1SRCSMN1; SMN2
SCHEMBL27938577 0.86 PRMT5 (0.49) DNPH1P2RY2P2RY1SRCSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7575901-B2 Propagating escherichia mutant which produces 5'-inosinic acid or 5'-guanylic acid; identifying nucleotidase gene associated with generating nucleoside 5'-phosphate esters AJINOMOTO CO., INC. (JP) 2009-08-18 US claimed
US-20080026428-A1 METHOD FOR PRODUCING NUCLEOTIDE BY FERMENTATION AJINOMOTO CO., INC. (JP) 2008-01-31 US claimed