Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | TYMS | P04818 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976137 | 0.89 | HSP90B1 (0.32) | — | |
| SCHEMBL6975217 | 0.87 | TP53 (0.39) | NPSR1L3MBTL1TP53RXFP1LMNA | |
| SCHEMBL6964947 | 0.87 | DHODH (0.34) | KMT2ATYMSLMNAALDH1A1DHFR | |
| SCHEMBL6973819 | 0.86 | TP53 (0.35) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL6972144 | 0.86 | IDO1 (0.35) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL6972417 | 0.86 | TP53 (0.39) | MEN1KMT2ATP53RXFP1TYMS | |
| SCHEMBL6973798 | 0.86 | MEN1 (0.40) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL6966003 | 0.86 | TYMS (0.37) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL6961885 | 0.86 | TP53 (0.37) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL7082939 | 0.86 | SMN1; SMN2 (0.31) | LMNAALDH1A1DHFRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |