Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025798 | 0.79 | PKM (0.39) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL3376906 | 0.77 | ALDH1A1 (0.38) | PKMKDM4ETHRBMEN1KMT2A | |
| SCHEMBL1263958 | 0.75 | CA1 (0.38) | HTTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL9913289 | 0.70 | KDM4E (0.39) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL29201875 | 0.69 | — | — | |
| SCHEMBL5606428 | 0.68 | PKM (0.61) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL14366070 | 0.67 | KDM4E (0.40) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL16125661 | 0.66 | KDM4E (0.44) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL8155896 | 0.65 | — | — | |
| SCHEMBL12064248 | 0.65 | PKM (0.75) | PKMKDM4ETHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068167-A2 | NOVEL TREATMENT FOR PATHOLOGIES ASSOCIATED WITH OXIDATIVE DAMAGE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-08-21 | — | — | WO | disclosed |