SCHEMBL7080684

SCHEMBL7080684

O=C(O)c1ccc(C(=O)O)c2c1C1CCC2CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
MAPT P10636 3/20 0.42
ALDH1A1 P00352 4/20 0.42
POLB P06746 1/20 0.42
ALOX15 P16050 1/20 0.42
ACMSD Q8TDX5 2/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
SELL P14151 1/20 0.39
SELP P16109 1/20 0.39
GPR35 Q9HC97 1/20 0.39
KDM5A P29375 1/20 0.39
KDM5B Q9UGL1 1/20 0.39
TSHR P16473 2/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618409 0.91 CYP1A2 (0.41) CYP1A2MAPTALDH1A1POLBALOX15
SCHEMBL9618410 0.91 CYP1A2 (0.41) CYP1A2MAPTALDH1A1POLBALOX15
SCHEMBL3425168 0.89 ACMSD (0.47) CYP1A2MAPTALDH1A1POLBALOX15
SCHEMBL18486812 0.89 ESR2 (0.42) CYP1A2MAPTALDH1A1POLBALOX15
SCHEMBL812111 0.89 ACMSD (0.53) CYP1A2ACMSDKDM5AKDM5BSMN1; SMN2
SCHEMBL1500383 0.86 ALDH1A1 (0.50) MAPTALDH1A1POLBALOX15KEAP1
SCHEMBL3427421 0.80 TSHR (0.45) ALDH1A1POLBTSHRSMN1; SMN2KDM4E
SCHEMBL14744374 0.80 CYP1A2 (0.48) CYP1A2MAPTALDH1A1POLBALOX15
SCHEMBL7191529 0.79 SERPINE1 (0.36) CYP1A2ALDH1A1TSHRSMN1; SMN2CASP1
SCHEMBL4395937 0.79 NOTUM (0.47) MAPTALDH1A1POLBALOX15KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6638893-B2 Element comprising dye-receiving layer, microvoided layer of continuous phase polyester matrix with dispersed crosslinked organic microbeads, microvoided layer of polyester matrix with dispersed immiscible noncrosslinked polymer particles EASTMAN KODAK COMPANY 2003-10-28 US disclosed
US-20030144146-A1 Thermal dye transfer receiver element with microvoided support EASTMAN KODAK COMPANY 2003-07-31 US disclosed
US-20030138581-A1 Voided articles EASTMAN KODAK COMPANY 2003-07-24 US disclosed
EP-1323541-A2 Thermal dye transfer receiver element with microvoided support EASTMAN KODAK COMPANY (US) 2003-07-02 EP disclosed