Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8062744 | 1.00 | THRA (0.41) | THRATHRBLMNATLR8XDH | |
| SCHEMBL3139330 | 0.92 | ESR1 (0.38) | THRATHRBLMNATLR8XDH | |
| SCHEMBL13374133 | 0.92 | ESR1 (0.38) | THRATHRBLMNATLR8XDH | |
| SCHEMBL2778642 | 0.89 | THRA (0.47) | THRATHRBTLR8XDHHTT | |
| SCHEMBL4622068 | 0.82 | HTR2A (0.49) | THRATHRBHTR2ATAAR1 | |
| SCHEMBL5073881 | 0.81 | THRA (0.47) | THRATHRBLMNATLR8XDH | |
| SCHEMBL11957249 | 0.80 | HTR2A (0.37) | LMNATDP1PRKDCPTPN1MEN1 | |
| SCHEMBL3130075 | 0.79 | THRA (0.41) | THRATHRBTLR8XDHHTT | |
| SCHEMBL8592803 | 0.79 | THRA (0.41) | THRATHRBTLR8XDHHTT | |
| SCHEMBL7080656 | 0.79 | THRA (0.42) | THRATHRBTLR8XDHHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815156-B1 | OLIGO-p-PHENYLENE-UNIT-CONTAINING POLYMERS, PROCESS FOR THEIR PRODUCTION AND THEIR USE | COVION ORGANIC SEMICONDUCTORS (DE) | 2003-07-09 | — | — | EP | disclosed |
| US-6114490-A | ELECTROLUMINESCENCE MATERIALS | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |