Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 11/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130075 | 0.90 | THRA (0.41) | THRATHRBHTR2ATAAR1HTR2C | |
| SCHEMBL2778642 | 0.89 | THRA (0.47) | THRATHRBHTR2ATAAR1TLR8 | |
| SCHEMBL4622068 | 0.82 | HTR2A (0.49) | THRATHRBHTR2ATAAR1HTR2C | |
| SCHEMBL5073881 | 0.81 | THRA (0.47) | THRATHRBTLR8XDHHTT | |
| SCHEMBL8592803 | 0.79 | THRA (0.41) | THRATHRBTLR8XDHHTT | |
| SCHEMBL8062744 | 0.79 | THRA (0.41) | THRATHRBHTR2ATAAR1TLR8 | |
| SCHEMBL7080828 | 0.79 | THRA (0.41) | THRATHRBHTR2ATAAR1TLR8 | |
| SCHEMBL3134444 | 0.78 | THRA (0.34) | THRATHRBHTR2ATAAR1TLR8 | |
| SCHEMBL13374131 | 0.77 | THRA (0.36) | THRATHRBHTR2ATAAR1TLR8 | |
| SCHEMBL1956731 | 0.76 | LMNA (0.43) | THRATHRBHTR2ATAAR1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815156-B1 | OLIGO-p-PHENYLENE-UNIT-CONTAINING POLYMERS, PROCESS FOR THEIR PRODUCTION AND THEIR USE | COVION ORGANIC SEMICONDUCTORS (DE) | 2003-07-09 | — | — | EP | disclosed |
| US-6114490-A | ELECTROLUMINESCENCE MATERIALS | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |