SCHEMBL4622068

SCHEMBL4622068

COc1cc(Br)c(OCCC(C)C)cc1Br

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.49
TAAR1 Q96RJ0 3/20 0.49
HTR2C P28335 1/20 0.43
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2778642 0.92 THRA (0.47) HTR2ATAAR1THRATHRB
SCHEMBL5073881 0.84 THRA (0.47) THRATHRB
SCHEMBL3130075 0.82 THRA (0.41) HTR2ATAAR1HTR2CTHRATHRB
SCHEMBL8592803 0.82 THRA (0.41) THRATHRB
SCHEMBL7080828 0.82 THRA (0.41) HTR2ATAAR1THRATHRB
SCHEMBL7080656 0.82 THRA (0.42) HTR2ATAAR1HTR2CTHRATHRB
SCHEMBL8062744 0.82 THRA (0.41) HTR2ATAAR1THRATHRB
SCHEMBL1956731 0.79 LMNA (0.43) HTR2ATAAR1THRATHRB
SCHEMBL17089284 0.79 L3MBTL1 (0.47) HTR2ATAAR1HTR2C
SCHEMBL13212631 0.77 THRA (0.40) THRATHRBMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4346771-A1 NANOTECHNOLOGICAL PLATFORM BASED ON POLYURETHANE/POLYUREA CHEMISTRY TO FURNISH WATER-OIL-WATER MULTI WALLED AND FUNCTIONALIZABLE NANOCAPSULES AND THEIR PREPARATION PROCESS Ecopol Tech, S.L. (ES) 2024-04-10 EP disclosed
WO-2022253483-A1 NANOTECHNOLOGICAL PLATFORM BASED ON POLYURETHANE/POLYUREA CHEMISTRY TO FURNISH WATER-OIL-WATER MULTI WALLED AND FUNCTIONALIZABLE NANOCAPSULES AND THEIR PREPARATION PROCESS ECOPOL TECH S.L. (ES) 2022-12-08 WO disclosed
EP-3255172-B1 THERMALLY DISSIPATIVE ARTICLE AND METHOD OF FORMING A THERMALLY DISSIPATIVE ARTICLE GEN ELECTRIC (US) 2021-05-19 EP disclosed
US-10145000-B2 Thermally dissipative article and method of forming a thermally dissipative article GENERAL ELECTRIC COMPANY (US) 2018-12-04 US disclosed
US-20170342540-A1 THERMALLY DISSIPATIVE ARTICLE AND METHOD OF FORMING A THERMALLY DISSIPATIVE ARTICLE GE INFRASTRUCTURE TECHNOLOGY LLC 2017-11-30 US disclosed
EP-1310514-B1 A silane copolymer and process for preparing the same BARD INC C R (US) 2008-09-10 EP disclosed
EP-1948605-A2 MODULATORS OF THE H3 RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO Arena Pharmaceuticals, Inc. (US) 2008-07-30 EP disclosed
EP-1277824-B1 Polymeric fluorescent substance and polymer light-emitting device using the same SUMITOMO CHEMICAL CO (JP) 2008-04-09 EP disclosed
US-7258932-B2 Polymeric fluorescent substrate and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-08-21 US disclosed
WO-2007061741-A2 MODULATORS OF THE H3 RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2007-05-31 WO disclosed
US-5661020-A CARBOXYLATION; ACTIVATION; COVALENTLY ATTACHING TO SUPEROXIDE DISMUTASE SANOFI (FR) 1997-08-26 US disclosed
US-5661020-A CARBOXYLATION; ACTIVATION; COVALENTLY ATTACHING TO SUPEROXIDE DISMUTASE SANOFI (FR) 1997-08-26 US disclosed
US-5532150-A IMMOBILIZED SUPEROXIDE DISMUTASE STERLING WINTHROP, INC. (US) 1996-07-02 US disclosed
US-5532150-A IMMOBILIZED SUPEROXIDE DISMUTASE STERLING WINTHROP, INC. (US) 1996-07-02 US disclosed
US-5529915-A CARBOXYLATION; ACTIVATION; SOLUBILIZING; BUFFERING STERLING WINTHROP INC. (US) 1996-06-25 US disclosed
US-5389381-A Administering superoxide dismutase bound to low diol polyoxyethylene glycol with buffers and protective cyclodextrins STERLING WINTHROP INC. (US) 1995-02-14 US disclosed
EP-0614666-A1 Lyophilized polyalkylene oxide modified protein and polypeptide complexes with cyclodextrin STERLING WINTHROP INC. (US) 1994-09-14 EP disclosed
US-5334382-A A freez dried peptide resins is made from a buffer solution mixture containing a low density polyether conjugated with an enzyme; storage stability, long shelf life STERLING WINTHROP INC. (US) 1994-08-02 US disclosed
US-5298410-A Conjugated with superoxide dismutase protein STERLING WINTHROP INC. (US) 1994-03-29 US disclosed
EP-0584876-A2 Low diol polyalkylene oxide biologically active proteinaceous substances STERLING WINTHROP INC. (US) 1994-03-02 EP disclosed