Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7177931 | 0.88 | ABL1 (0.40) | CYP1A2CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7173359 | 0.88 | ALDH1A1 (0.42) | CYP1A2CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7463501 | 0.79 | CA12 (0.41) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL7174222 | 0.78 | HPD (0.33) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7707415 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KDM4EHSD17B10POLBTSHR | |
| SCHEMBL7172627 | 0.72 | ABL1 (0.45) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL8435434 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10POLBTSHR | |
| SCHEMBL7467250 | 0.68 | ABL1 (0.47) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL9118991 | 0.67 | ABL1 (0.39) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL967909 | 0.66 | CYP3A4 (0.44) | ALDH1A1KDM4ETSHRMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960100-B1 | SUBSTITUTED 4-BENZOYL-PYRAZOLES | BASF AG (DE) | 2003-07-09 | — | — | EP | disclosed |
| US-6576596-B1 | Compatible with crop plants | BASF AKTIENGESELLSCHAFT (DE) | 2003-06-10 | — | — | US | disclosed |
| US-6462240-B2 | FROMING 2-LITHIOBENZOTRIFLORIDE FROM BENZOTRIFLUORIDE AND ALKYLLITHIUM | DOW AGROSCIENCES LLC | 2002-10-08 | — | — | US | disclosed |
| EP-0958276-B1 | SUBSTITUTED 2-BENZOYL-CYCLOHEXAN-1,3-DIONES WITH HERBICIDAL EFFECT | BASF AG (DE) | 2002-03-13 | — | — | EP | disclosed |
| US-20020010375-A1 | Process for the selective deprotonation and functionalization of 3-substituted benzotrifluorides | CORTEVA AGRISCIENCE LLC | 2002-01-24 | — | — | US | disclosed |
| EP-1173420-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | Novuspharma S.p.A. (IT) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000053581-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | NOVUSPHARMA S.P.A. (IT) | 2000-09-14 | — | — | WO | disclosed |
| US-6028035-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-22 | — | — | US | disclosed |
| EP-0960100-A1 | SUBSTITUTED 4-BENZOYL-PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0958276-A1 | SUBSTITUTED 2-BENZOYL-CYCLOHEXAN-1,3-DIONES WITH HERBICIDAL EFFECT | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998029392-A1 | SUBSTITUTED 4-BENZOYL-PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-07-09 | — | — | WO | disclosed |
| WO-1998029384-A1 | SUBSTITUTED 2-BENZOYL-CYCLOHEXAN-1,3-DIONES WITH HERBICIDAL EFFECT | BASF AKTIENGESELLSCHAFT (DE) | 1998-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010375-A1 | Process for the selective deprotonation and functionalization of 3-substituted benzotrifluorides | BPTF, FGFR2, FGFR4 | CYP1A2 1167/4885CYP2D6 1281/4885CYP2C9 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.