Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081220 | 0.87 | LMNA (0.46) | LMNAKMT2A | |
| SCHEMBL7081235 | 0.87 | LMNA (0.44) | LMNAKMT2A | |
| SCHEMBL7081222 | 0.87 | LMNA (0.43) | LMNAKMT2A | |
| SCHEMBL7081886 | 0.83 | LMNA (0.42) | LMNAKMT2A | |
| SCHEMBL7087231 | 0.81 | LMNA (0.46) | LMNAKMT2APOLB | |
| SCHEMBL7080977 | 0.80 | — | — | |
| SCHEMBL7615093 | 0.79 | LMNA (0.37) | LMNAKMT2APOLB | |
| SCHEMBL9423194 | 0.78 | LMNA (0.38) | LMNAKMT2A | |
| SCHEMBL7080891 | 0.78 | LMNA (0.36) | LMNAKMT2A | |
| SCHEMBL7081978 | 0.77 | CA2 (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | claimed |
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | disclosed |
| US-5336690-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1994-08-09 | — | — | US | disclosed |
| US-5254715-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1993-10-19 | — | — | US | disclosed |