SCHEMBL7081222

SCHEMBL7081222

CC(C)OC(=O)N(c1ccccc1)S(=O)(=O)Nc1c(C(C)C)cccc1C(C)C

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7080899 0.87 LMNA (0.47) LMNAKMT2A
SCHEMBL9452039 0.80
SCHEMBL7081220 0.77 LMNA (0.46) LMNAKMT2A
SCHEMBL7081235 0.77 LMNA (0.44) LMNAKMT2A
SCHEMBL7086451 0.75 ALDH1A1 (0.42) LMNAKMT2A
SCHEMBL7085482 0.74 ALDH1A1 (0.41) LMNAKMT2A
SCHEMBL7087231 0.74 LMNA (0.46) LMNAKMT2A
SCHEMBL7080977 0.73
SCHEMBL7081886 0.73 LMNA (0.42) LMNAKMT2A
SCHEMBL9452030 0.71 ATM (0.39) LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0592439-B1 AMINOSULFONYL CARBAMATES WARNER LAMBERT CO (US) 2003-07-30 EP disclosed