Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080086 | 0.90 | REN (0.31) | REN | |
| SCHEMBL6043104 | 0.89 | REN (0.33) | RENKRASKDM4EMEN1ALDH1A1 | |
| SCHEMBL6041853 | 0.83 | REN (0.33) | REN | |
| SCHEMBL7076917 | 0.80 | REN (0.33) | REN | |
| SCHEMBL6042443 | 0.79 | REN (0.35) | REN | |
| SCHEMBL7075270 | 0.77 | MEN1 (0.42) | RENMEN1KMT2A | |
| SCHEMBL7080459 | 0.77 | NPC1 (0.36) | REN | |
| SCHEMBL7080839 | 0.77 | PDCD1 (0.38) | REN | |
| SCHEMBL27502531 | 0.76 | PRMT5 (0.36) | REN | |
| SCHEMBL6041417 | 0.76 | PDCD1 (0.41) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |