Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076917 | 0.90 | REN (0.33) | REN | |
| SCHEMBL7080914 | 0.90 | REN (0.33) | REN | |
| SCHEMBL7080839 | 0.86 | PDCD1 (0.38) | REN | |
| SCHEMBL7081100 | 0.85 | PRMT5 (0.33) | REN | |
| SCHEMBL7080459 | 0.85 | NPC1 (0.36) | REN | |
| SCHEMBL7079646 | 0.84 | REN (0.34) | REN | |
| SCHEMBL6043104 | 0.84 | REN (0.33) | REN | |
| SCHEMBL7083552 | 0.83 | REN (0.33) | REN | |
| SCHEMBL7082266 | 0.83 | REN (0.38) | REN | |
| SCHEMBL7079374 | 0.83 | MAPT (0.41) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |